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Bloom Burton & Co.
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  • Canada in Science – September 1, 2017
    Welcome to your Canada in Science Review for September 1st, 2017! Neuron. 2017 Aug 16;95(4):808-816.e9. TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics. Nature. 2017 Aug 30. doi: 10.1038/nature23666. Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy. J Allergy Clin Immunol. 2017 Aug 18....
Bloom Burton & Co.
Bloom Burton & Co.
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  • My Introduction to Industry
    My Introduction to Industry By Wayne Schnarr   In this post, Wayne switches gears from talking about his time in academia, to his foray into industry which marked the beginning of his career in manufacturing. My first industrial position was in 1978 as a research chemist at the Canada Packers Research Centre and my first
Bloom Burton & Co.
Bloom Burton & Co.
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  • Canada in Science – August 18, 2017
    Welcome to your Canada in Science Review for August 18th, 2017! Proc Natl Acad Sci U S A. 2017 Aug 7. doi: 10.1073/pnas.1704310114. Near-atomic resolution cryoelectron microscopy structure of the 30-fold homooligomeric SpoIIIAG channel essential to spore formation in Bacillus subtilis.   Nat Genet. 2017 Aug 7. doi: 10.1038/ng.3930. TMPRSS2-ERG fusion co-opts master transcription factors and activa...
Bloom Burton & Co.
Bloom Burton & Co.
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  • The Bioscience Sector in Atlantic Canada
    The Bioscience Sector in Atlantic Canada By Matthew Johnson   As Canada’s leading healthcare-focused investment firm, Bloom Burton & Co. seeks to develop strong connections to health and bioscience innovation clusters across the country. In this new blog series, Matthew Johnson, VP Business Development, will recount experiences traveling across this “Health Innovation Nation”. There’s no
Bloom Burton & Co.
Bloom Burton & Co.
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  • Are Canadian Universities Excelling at Teaching?
    Are Canadian Universities Excelling at Teaching? By Wayne Schnarr In his previous post, Wayne tackled the question of whether universities were doing enough to balance their teaching priorities with their research commitments. In this post he talks about excellence in teaching, and proposes a new teaching model that ensures university students are taught not only
Bloom Burton & Co.
Bloom Burton & Co.
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  • Canada in Science – August 4, 2017
    Welcome to your Canada in Science Review for August 4th, 2017!   Immunity. 2017 Jul 18;47(1):93-106.e7. Peroxisome-Mediated Metabolism Is Required for Immune Response to Microbial Infection. Stem Cells. 2017 Jul 31. doi: 10.1002/stem.2655. Brief Report: Human Acute Myeloid Leukemia Reprograming to Pluripotency Is a Rare Event and Selects for Patient Hematopoietic Cells Devoid of Leukemic Mutations...
Bloom Burton & Co.
Bloom Burton & Co.
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  • Canada in Science – July 21, 2017
    Welcome to your Canada in Science Review for July 21st, 2017!   Nat Med. 2017 Jul 17. doc: 10.1038/nm.4367. Correction of a splicing defect in a mouse model of congenital musculardystrophy type1A using a homology-directed-repair independent mechanism. Cell. 2017 Jul 13;170(2):324-339.e23. Regulatory Expansion in Mammals of Multivalent hnRNP Assemblies that Globally Control Alternative Splicing. Ce...
Bloom Burton & Co.
Bloom Burton & Co.
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  • Q2 Share Price Performance in 2017 – Part 3
    In the final instalment of this analysis, I will comment on the Q2 and H1 2017 share price performance of the group of 65 companies with share prices of between $0.10 and $0.99 to start 2017 (excludes Immunotec which was taken private in Q2). Overall, Tier 2 Canadian healthcare companies had a moderately negative performance
Bloom Burton & Co.
Bloom Burton & Co.
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  • Are Canadian Universities Balancing and Excelling at Teaching and Research?
    Are Canadian Universities Balancing and Excelling at Teaching and Research? By Wayne Schnarr In this article, Wayne looks at how universities have changed through the years, from when he first graduated in 1967, to today. He ponders over the always relevant but sometimes controversial question of whether universities are doing enough to balance their dual
Bloom Burton & Co.
Bloom Burton & Co.
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  • Q2 Share Price Performance in 2017 – Part 2
              Overall, Tier 1 Canadian Healthcare Companies had a negative performance driven by one group of companies. In this article, I am going to comment on the Q2 and H1 performance of the group of 53 companies with share prices of $1.00 or more to start 2017. Q2 2017 Summary Decliners almost
Bloom Burton & Co.
Bloom Burton & Co.
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  • Canada in Science – July 11, 2017
    Welcome to your Canada in Science Review for July 11th, 2017!   Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7124-7129. Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity. Curr Biol. 2017 Jun 20. pii: S0960-9822(17)30650-4. Differential Control of Dopaminergic Excitability and Locomotion by Cholinergic Inputs in Mouse Substantia Nigra. PLoS Biol. 2017 Jun 20;15(6):e20...
Bloom Burton & Co.
Bloom Burton & Co.
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  • Q2 Share Price Performance in 2017 – Part 1
      Overall, Q2 2017 share price performance in the sector was mixed with high volatility. A top-line look at the combined Tier 1 and 2 share price changes shows that despite a poor Q2 (-4.9%), the first half was still positive (+4.9%). However, a topline look always needs to be followed by a detailed analysis. The
Bloom Burton & Co.
Bloom Burton & Co.
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  • Undergraduates, are you asking the right questions?
    Undergraduates, are you asking the right questions? By Wayne Schnarr In Part 2 of this blog series, I assumed that my Ph.D. was the start of my career, omitting the many questions to be asked and decisions to be made at the undergraduate level. In the late 1960s, a high school diploma could have been
Bloom Burton & Co.
Bloom Burton & Co.
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  • Canada in Science – June 23, 2017
    Welcome to your Canada in Science Review for June 23rd, 2017! J Mol Biol. 2017 Jun 3. pii: S0022-2836(17)30272-3. Molecular Basis for K63-Linked Ubiquitination Processes in Double-Strand DNA Break Repair: A focus on Kinetics and Dynamics. Nat Med. 2017 Jun;23(6):674-677. Metformin ameliorates core deficits in a mouse model of fragile X syndrome. J Mol Biol. 2017 Jun 3.
Bloom Burton & Co.
Bloom Burton & Co.
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  • Why Did I Get a PhD and What Can You Do With One?
    Why Did I Get a PhD and What Can You Do With One?  By Wayne Schnarr Why did I go to graduate school? I had a job offer from Agriculture Canada, I would probably have been accepted into medical school at U.B.C. and I was offered a 4 year NRC Post-Graduate Scholarship (University of Victoria
Bloom Burton & Co.
Bloom Burton & Co.
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  • Beyond the Bench
    LOOKING BACK ON A CAREER IN CANADIAN HEALTHCARE (Part 1) In early 2017, I made a personal decision to wind down all my active work with Canadian healthcare companies and focus on retirement, family, hobbies and travel. Many people remind me of my similar attempt at this in 2008 when I ‘got retired’ from my
Bloom Burton & Co.
Bloom Burton & Co.
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  • Canada in Science – June 9, 2017
    Welcome to your Canada in Science Review for June 9th, 2017! Nat Nanotechnol. 2017 Apr 24. doi: 10.1038/nnano.2017.56 Peptide-MHC-based nanomedicines for autoimmunity function as T-cell receptor micro clustering devices. Nature. 2017 Apr 27;544(7651):493-497. SLAMF7 is critical for phagocytosis of hematopoietic tumour cells via Mac-1 integrin.   Cell. 2017 Mar 23;169(1):58-71.e14. A Viral Immunoev...
Bloom Burton & Co.
Bloom Burton & Co.
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  • Three Finalists Announced for the Inaugural Bloom Burton Award
    Annual Award to Recognize the Most Significant Contributor to Canada’s Healthcare Industry TORONTO, May 8, 2017 – Bloom Burton & Co. (“Bloom Burton”), Canada’s leading healthcare-specialized investment banking firm, is pleased to announce the three finalists for the inaugural Bloom Burton Award. The finalists are: Allen Eaves, Founder, President and CEO of STEMCELL Technologies: Anthony Giovinazzo...
Bloom Burton & Co.
Bloom Burton & Co.
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  • Hamilton Thorne Announces Acquisition of Gynemed GmbH & Co.
    Click here to read the full press release. Source: Newswire – April 28, 2017 BEVERLY, MA and TORONTO, ON — (April 28, 2017) – Hamilton Thorne Ltd. (TSX VENTURE: HTL) (“Hamilton Thorne” or the “Company”), a leading provider of precision instruments, consumables, software and services to the Assisted Reproductive Technologies (ART) and developmental biology research

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