Illumina, Inc. is an American company incorporated in April 1998 that develops, manufactures and markets integrated systems for the analysis of genetic variation and biological function. In 2014, Illumina was named the world's smartest company by MIT Technology Review. Using its technologies, the company provides a line of products and services that serve the sequencing, genotyping and gene expression markets. This technology had purportedly by 2013 reduced the cost of sequencing a human genome to US$4,000, down from a price of US$1 million in 2007. Customers include genomic research centers, pharmaceutical companies, academic institutions, clinical research organizations and biotechnology companies. Its tools provide researchers with the capability to perform genetic tests needed to extract medical information from advances in genomics and proteomics. Its headquarters are located in San Diego, California.