Thermo Fisher Scientific is an American multinational biotechnology product development company, created in 2006 by the merger of Thermo Electron and Fisher Scientific. In April 2013, after a competitive bidding with Hoffmann-La Roche, Thermo Fisher acquired Life Technologies Corp for $13.6 billion in a deal that would rank the firm as one of the leading companies in the genetic testing and precision laboratory equipment markets.

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Thermo Fisher Scientific
Thermo Fisher Scientific
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  • You may know about our simple load-and-go reagents, fast sequencing, and automated workflow on the Ion S5 Systems. Well, we’ve just taken our platform to the next level. With the Ion GeneStudio S5 Systems, we’ve designed a system with the range and speed of data output to provide the versatility and scalability to handle multiple The post Meet the New Ion GeneStudio S5 Systems appeared first on Be...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • As the manager of the molecular genetic laboratory in the department of clinical genetics at Rigshospitalet in Copenhagen, Denmark, Morten Dunoe and his colleagues are responsible for the analyses of myriad sequencing projects. In fact, they perform analysis of more than 200 genetic disorders, with a consistent focus on performance and quality. So when he The post Innovation—Ingrained in the DNA o...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Do you use metal detection and X-ray inspection technology to help ensure that the packaged food products you produce and that your customers choose from a very crowded grocery shelf do not contain physical contaminants? If not, have you been afraid to ask about the potential problem? If you are in the food processing industry, The post What You Need to Know About Packaged Food Metal Detection an...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • The United States Nuclear Regulatory Commission (USNRC) defines a dirty bomb as one type of a radiological dispersal device (RDD) that combines conventional explosives, such as dynamite, with radioactive material.  According to the USNRC, a dirty bomb is in no way similar to a nuclear weapon or nuclear bomb.  The fact sheet explains: A nuclear The post What’s the Difference Between a Dirty Bomb an...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • When a mine operation closes, many new operations go into effect to restore the site back to its original state. One issue addressed by mine site remediation is tailings, mineral waste products that may have been dumped in or near water and contaminate the surrounding area. Novel reprocessing technologies are emerging to extract valuable metals from The post New Revenue from Old Mines Through Rene...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • It’s highly probable that you’re already acutely aware of the need for contamination-free cell cultures. To achieve this, you probably use water of a sufficient purity, wipe down surfaces with 70% ethanol and bleach, avoid cross-contamination with other cell types and have become adept at not breathing, coughing or touching your cultures! However, what about The post How Clean is your CO2 Incubato...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Eliminate cell culture contamination for maximum sample protection is one of the main challenges facing cell culture laboratories. Whilst moist heat methods are ideal for rapid sterilization of wrapped instruments and other packaged items in hospital settings, dry heat sterilization has emerged as the technology of choice for the decontamination of equipment surfaces. Spotless clean The post Beat ...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Traditionally, cells have been grown in monolayer cultures on a solid, non-porous surfaces such as polystyrene. While this model allows all cells to live in a uniform environment, it doesn’t mimic the complex intracellular environment that cells experience in vivo. A more physiologically relevant model is a three-dimensional culture. In this environment, cells are able The post Growing 3D Cell Cul...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Physiological conditions are optimal for the growth of primary cells, stem cells and 3D cultures. That’s why it’s important to make sure your incubator closely resembles these conditions as they are in vivo. Incubator parameters vary widely; and while you may not have control over all, there are a few factors you have some control over The post Creating Ideal incubator conditions for optimal cell ...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Defeating edge effect is paramount to achieving consistency in cell culture. Consistency is needed for accurate and effective cell culture research, and is especially important for those using cell cultures for disease models and drug screening, where reliability is paramount. There are numerous factors that can impact consistency, including contamination, spontaneous differentiation, poor growth ...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Parkinson’s disease is thought to be caused by the death of dopaminergic cells in the substantia nigra region of the midbrain. While treatments exist to reduce the severity of some symptoms, the disease remains poorly understood and there is a great need for improved medical treatment. Since the disease is thought to involve cell death, The post Consistent Cell Culture for Parkinson’s Research app...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Billions of dollars are invested globally into the clinical approval of new drug compounds, but only a small handful of new chemical entities are approved by the Food and Drug Administration (FDA) each year. Cell-based assays have been a key component in streamlining the drug development process, helping drugs be brought to the market in The post Current Trends in Cell-based Assays and Drug Discov...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Mimicking an in vivo environment is one of the most difficult tasks in cell culture, but a CO2 incubator can make the process much easier by maintaining stable environmental conditions. Cells are very sensitive to changes in temperature, pH, and humidity, and constantly opening and closing the door can result in atmospheric fluctuations. These changes can affect The post Taking Care of Your CO2 In...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Cell culture techniques have been around since the mid-20th century and the field continues to expand into a range of areas, such as cancer research and drug screening. It’s likely that you’re already using cell culture as a regular research tool in the lab, but in such a rapidly evolving field it can be difficult The post How Can Cell Culture Help You? appeared first on Advancing Cell Culture.

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • It’s been well established that culturing cells in three-dimensions is much more representative of the in vivo environment than traditional two-dimensional cultures. The multicellular arrangement allows cells to interact with each other and the extracellular matrix (ECM), providing a much better understanding of cellular complexities, particular in cancer and stem cell research – an area The post ...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Colonoscopies are currently the best method to diagnose colorectal cancer (CRC). A less invasive method, the fecal occult blood test (FOBT), can detect CRC in average-risk individuals; however, it is only 50% effective. With prognosis tied to early diagnostics and a rise in CRC worldwide, researchers such as Peltier et al. seek new diagnostic biomarkers in blood.1 The post New Diagnostic Biomarker...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Dehydroepiandrosterone (DHEA); 4-androstene-3,17-dione (AD); and testosterone are androgenic 19-carbon steroids that serve as precursors for other male and female sex hormones. They influence sex-specific and sexually dimorphic processes such as spermatogenesis, muscle growth and neural development. In humans, the adrenal glands primarily produce DHEA, while adrenals and gonads both produce AD. Th...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • The Chromosome-centric Human Proteome Project (C-HPP), an initiative of the Human Proteome Organization (HUPO), seeks to identify all proteins encoded by genes as a bridge between the worlds of genomics and proteomics. However, problems exist in that researchers have not yet identified some predicted gene products. Choong et al. (2015) examined possible informatics issues contributing The post Whe...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Neurotransmitters (i.e., biogenic amines and amino acids) are common chemical messengers that promote intersynaptic signal transmission, thereby participating in brain function. Direct knowledge of brain structure and function is critical for understanding and treating brain disorders like addiction, depression and neurodegenerative disease. Until now, researchers relied on two non-ideal strategie...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Zheng et al. performed top-down mass spectrometric proteomic analysis to characterize human histone H3 proteoforms in primary multiple myeloma cell lines.1 Using malignant cells that overexpress histone methyltransferase MMSET, the researchers investigated driver mutations that contribute to modification of histones responsible for epigenetic control in disease. Although researchers understand tha...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  •   A team of researchers from Spain and Sweden recently examined the effects of rosemary (Rosmarinus officinalis L.) on colon cancer cell proliferation. It may seem like a feeble treatment for something as serious as cancer, but Valdés et al. explain that rosemary has documented health benefits, with its medicinal uses dating back thousands of The post Effects of Rosemary Extract on Colon Cancer Ce...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Huntington’s disease (HD) is a genetic neurodegenerative disorder. With a median age of onset of 40 years, patients will typically live 15–20 years following their diagnosis. In addition to this unfortunately bleak outlook, there are no current therapies to slow disease progression, and little is known regarding HD pathophysiological mechanisms. Graham et al. (2016) posit The post Novel Huntington...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • The outbreak of Zika virus (ZIKV) reported in Brazil earlier this year is associated with higher incidence of babies born with microcephaly. Liang et al. (2016) recently presented evidence of ZIKV protein disruption of neuronal signaling pathways, which inhibits development in fetal neuronal stem cells (fNSCs), showing both the molecular basis behind infection and indicating potential The post Zik...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Bile acids may be a useful tool for diagnosis of hepatobiliary diseases in infants. Further, bile acid concentration abnormalities can be associated with intrahepatic cholestasis, nondiabetic metabolic syndrome and type 2 diabetes mellitus. The human body synthesizes bile acids from cholesterol; synthesis occurs in the liver cells. This two-step process involves the formation of two primary bile a...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • Sun et al. (2016) present a biomarker discovery study that searches for serum proteins as indicators of altered metabolic function in patients with lung cancer.1 Their method includes protein elution plate (PEP) technology, with mass spectrometric (MS) proteomic analysis for identification.  One of the pathophysiological mechanisms employed by cancer cells is a shift on cellular The post Lung Canc...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • A recent announcement by the United Kingdom’s Food Standards Agency made runny eggs safe once more for vulnerable sectors of the population. More than 30 years after a shock remark from junior health minister Edwina Currie sank the British egg industry, UK Lion Mark eggs are now effectively free from salmonella and thus safe for The post ‘Salmonella-Free’ UK Lion Mark Eggs: Runny Eggs for All appe...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • It’s never too early in the year for Northwest Food & Beverage World. The event will be held January 8–10 in Portland, Oregon, USA. The organization promotes this regional show as having a national impact on the food and beverage manufacturing industry, as it brings together the premier vendors of packaging and machinery and the key The post Powerful Product Inspection Technology at NWFPA appeared...

Thermo Fisher Scientific
Thermo Fisher Scientific
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  • As 2017 draws to a close, the Examining Food team would like to wish all our readers a peaceful and relaxing holiday. For those who would like to take the opportunity to catch up on some posts you might have missed, we’ve collected some of our top stories from the year below. Happy reading! Is The post Holiday Reading from Examining Food appeared first on Examining Food.

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